Syracuse vs.  Virginia odds, prediction, line: 2022 Week 4 college football picks by model on 51-43 run

Syracuse vs. Virginia odds, prediction, line: 2022 Week 4 college football picks by model on 51-43 run

The Syracuse Orange and Virginia Cavaliers square off on Friday in the sixth all-time meeting between ACC foes. Virginia leads the all-time series on the heels of three straight wins over Syracuse. The Orange are enjoying a fantastic start in 2022, winning the first three games, while Virginia is 2-1. The Cavaliers are playing their first ACC game of the season, and the Orange are 1-0 in conference play.

kick-off is scheduled for 7 p.m. ET. Caesars Sportsbook lists the Orange as 9-point favorites at home, and the total number of points Vegas thinks will be scored, or the over/under, is 54 in the latest Virginia vs. Syracuse odds. Before making any Virginia vs. Syracuse picks, you need to see the college football predictions and betting advice from SportsLine’s advanced computer simulation model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past six-plus years, the proprietary computer model has generated a stunning profit of more than $3,300 for $100 players on its top-rated college football picks against the spread. It enters Week 4 of the 2022 college football season on a 51-43 run on all top-rated college football spread and money-line picks that dates back to 2021. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on Virginia vs. Syracuse and just locked in its picks and CFB predictions. You can head to SportsLine now to see the model’s picks. Now, here are several college football odds and betting lines for Syracuse vs. UVA:

  • Virginia vs. Syracuse spread: Syracuse -10
  • Virginia vs. Syracuse over/under: 54 points
  • Virginia vs. Syracuse money line: Syracuse -385, Virginia +300
  • VIR: The Cavaliers are 7-8 against the spread in the last 15 games
  • SYR: The Orange are 11-4 against the spread in the last 15 games
  • Virginia vs. Syracuse picks: See picks here

Featured Game | Syracuse Orange vs. Virginia Cavaliers

Why Virginia can cover

Virginia’s defense is stingy, and that comes in handy on the road in conference play. The Cavaliers have allowed only 18.3 points per game this season, and opponents are generating fewer than 200 passing yards per game against Virginia. Syracuse is operating at a high level through the air, but the Orange are averaging only 3.9 yards per carry, giving Virginia an avenue toward success.

On offense, Virginia is averaging 413.3 total yards per game, and the Cavaliers have exceeded 500 yards in two of three games. Virginia is solidly above-average on the ground, racking up 176.7 yards per game and 4.6 yards per carry. Quarterback Brennan Armstrong is a two-way threat with more than 1,000 career rushing yards, and pass-catcher Keytaon Thompson has more than 1,200 receiving yards since the start of the 2021 season. Syracuse’s defense is giving up a 73.5% completion rate to begin the 2022 campaign, and Armstrong is experienced and capable of explosiveness.

Why Syracuse can cover

Syracuse has real star power, beginning with Sean Tucker. The talented running back led the entire ACC with 1,496 rushing yards last season, and racked up 12 rushing touchdowns as well in 2021. Tucker also has 378 total yards this season, and quarterback Garrett Shrader is also off to a hot start. Shrader is averaging 9.2 yards per pass attempt with eight touchdowns and no interceptions, and he is also generating 67 rushing yards per game with three touchdowns on the ground. Syracuse is converting 44.1% of third down opportunities, and that is a big reason for the 3-0 start of the Orange.

On defense, Syracuse is yielding fewer than 17 points and 100 rushing yards per game, and the Orange are facing a Virginia offense that could be vulnerable. Virginia scored only three points and produced only 222 total yards in the only game against a Power 5 opponent in Illinois, and the Cavaliers are completing fewer than 55% of passes with more interceptions than passing touchdowns.

How to make Virginia vs. Syracuse picks

SportsLine’s model is leaning under on the point total, with both teams projected to throw at least one interception. The model also says one side of the spread hits in almost 60% of simulations. You can only see the model’s CFB picks at SportsLine.

So who wins Virginia vs. Syracuse? And which side of the spread hits in almost 60% of simulations? Visit SportsLine now to see which side of the Virginia vs. Syracuse spread you need to jump on Friday, all from the model that has crushed its college football picks, and find out.